{"id":32405,"date":"2020-07-07T07:40:45","date_gmt":"2020-07-07T06:40:45","guid":{"rendered":"https:\/\/www.filtrox.com\/?p=32405"},"modified":"2025-04-14T15:41:18","modified_gmt":"2025-04-14T14:41:18","slug":"maks","status":"publish","type":"post","link":"https:\/\/www.filtrox.com\/ch\/blog\/2020\/07\/07\/maks\/","title":{"rendered":"S\u00e4ugetierzellen und mAks Filtrationsl\u00f6sungen"},"content":{"rendered":"\n\n\n\n\n<p><img decoding=\"async\" class=\"alignnone lazyload\" title=\"Filtration von mAks und S\u00e4ugetierzellen\" data-src=\"https:\/\/www.filtrox.com\/wp-content\/uploads\/2020\/02\/header_mammalian-cells_mAbs.jpg\" alt=\"S\u00e4ugetierzellen und mAks Filtrationsl\u00f6sungen\" width=\"60%\" height=\"\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 1200px; --smush-placeholder-aspect-ratio: 1200\/518;\" \/><\/p>\n<table style=\"width: 70%; border-collapse: collapse; height: 0px;\">\n<tbody>\n<tr style=\"height: 0px;\">\n<td style=\"width: 70%; height: 0px;\">\n<h4><strong>Kl\u00e4rungsprozess mit Einweg- und traditionellem Verfahren<\/strong><\/h4>\n<p>Die fortlaufende Optimierung von S\u00e4ugetier-Zelllinien und Fermentationsprozessen f\u00fchrt zu h\u00f6heren Zelldichten\/Titern und h\u00f6heren Ausbeuten an monoklonalen Antik\u00f6rpern (mAks). Aufgrund dieser Optimierungen nimmt auch die Biomasse zu, einschliesslich der Zelltr\u00fcmmer und anderer Verunreinigungen, was eine Herausforderung f\u00fcr den Kl\u00e4rungs-\/Ernteschritt darstellt.<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 70%; border-collapse: collapse;\">\n<tbody>\n<tr>\n<td style=\"width: 70%;\">\n<p>Der konventionelle Kl\u00e4rungsprozess umfasst einen ersten und zweiten Kl\u00e4rungsschritt. Aufgrund potenziell hoher Scherkr\u00e4fte und der Notwendigkeit dieses Schritts zur Entfernung von Submikronpartikeln, ist die Tiefenfiltration ein obligatorischer Schritt vor dem Weiterleiten der Fl\u00fcssigkeit in den Abstrom.\u00a0<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr \/>\n<p><span style=\"color: #a46fd9;\"><span style=\"font-size: 24px;\"><b><span style=\"color: #a4c544;\">Dieses Verfahren vereint niedrige Betriebskosten mit betrieblicher Stabilit\u00e4t.<\/span><br \/><\/b><\/span><\/span><\/p>\n<hr \/>\n<p>\u00a0<\/p>\n<p>Weitere Informationen finden Sie auf unserer Webpage oder kontaktieren Sie unsere Filtrationsexperten:<\/p>\n<table style=\"width: 70%; border-collapse: collapse; height: 34px;\">\n<tbody>\n<tr style=\"height: 34px;\">\n<td style=\"width: 100%; background-color: #a4c544; vertical-align: middle; height: 34px;\"><span style=\"background-color: #a46fd9;\"><a style=\"background-color: #a46fd9;\" href=\"https:\/\/www.filtrox.com\/ch\/anwendungen\/filtration-life-sciences\/maks\/\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"aligncenter lazyload\" title=\"weitere Informationen \u00fcber die Filtration von S\u00e4ugetierzellen und mAk's\" data-src=\"https:\/\/www.filtrox.com\/wp-content\/uploads\/2020\/04\/Mehr.png\" alt=\"mehr erfahren\" width=\"117\" height=\"32\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 117px; --smush-placeholder-aspect-ratio: 117\/32;\" \/><\/a><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table style=\"width: 70%; border-collapse: collapse;\">\n<tbody>\n<tr>\n<td style=\"width: 100%; background-color: #b3d5e3; text-align: center; vertical-align: middle;\"><a href=\"https:\/\/www.filtrox.com\/ch\/kontakt\/fragen-an-filtrox-experten\/\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"alignnone lazyload\" title=\"Kontakt FILTROX\" data-src=\"https:\/\/www.filtrox.com\/wp-content\/uploads\/2019\/11\/Contact.gif\" alt=\"Contact button\" width=\"117\" height=\"32\" src=\"data:image\/svg+xml;base64,PHN2ZyB3aWR0aD0iMSIgaGVpZ2h0PSIxIiB4bWxucz0iaHR0cDovL3d3dy53My5vcmcvMjAwMC9zdmciPjwvc3ZnPg==\" style=\"--smush-placeholder-width: 117px; --smush-placeholder-aspect-ratio: 117\/32;\" \/><\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u00a0<\/p>\n<p><strong>LINKS UND DOWNLOADS:<\/strong><\/p>\n<p><a href=\"https:\/\/www.filtrox.com\/ch\/anwendungen\/filtration-life-sciences\/maks\/\" target=\"_blank\" rel=\"noopener noreferrer\">MEHR \u00dcBER DIE KL\u00c4RUNGS-L\u00d6SUNGEN F\u00dcR S\u00c4UGETIERZELLEN UND MAKs<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kl\u00e4rungsprozess mit Einweg- und traditionellem Verfahren Die fortlaufende Optimierung von S\u00e4ugetier-Zelllinien und Fermentationsprozessen f\u00fchrt zu h\u00f6heren Zelldichten\/Titern und h\u00f6heren Ausbeuten an monoklonalen Antik\u00f6rpern (mAks). Aufgrund dieser Optimierungen nimmt auch die Biomasse zu, einschliesslich der Zelltr\u00fcmmer und anderer Verunreinigungen, was eine Herausforderung f\u00fcr den Kl\u00e4rungs-\/Ernteschritt darstellt. Der konventionelle Kl\u00e4rungsprozess umfasst einen ersten und zweiten Kl\u00e4rungsschritt. Aufgrund &hellip; <a href=\"https:\/\/www.filtrox.com\/ch\/blog\/2020\/07\/07\/maks\/\" class=\"more-link\">Continue reading <span class=\"screen-reader-text\">S\u00e4ugetierzellen und mAks Filtrationsl\u00f6sungen<\/span> <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"advgb_blocks_editor_width":"","advgb_blocks_columns_visual_guide":"","footnotes":""},"categories":[455,104,509],"tags":[],"class_list":["post-32405","post","type-post","status-publish","format-standard","hentry","category-events-life-science-ch-2","category-news-ch","category-news-life-science-ch-2"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>mAKs und S\u00e4ugetierzellen - FILTROX Tiefenfiltration<\/title>\n<meta name=\"description\" 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